[2] Rockwood K.Vascular cognitive impairment and vascular dementia[J].J Neurol Sci,2002,23:203-204.
[3] Roman GC,Sachdev P,Royall DR,et al.,Vascular cognitive disorder.a new diagnostic category updating vascular cognitive impairment and vascular dementia[J].J Neurology,2000,54:447-51.
[4] Neuropathology Group.Medical Research Council Cognitive Function and Aging Study.Pathological correlates of late-onset dementia in a multicentre,community-based population in England and Wales[J].Lancet,2001, 357:169-75.
[5] Barker WW,luis CA,Kashuba A,et al.,Relative frequencies of Alzheimer disease,Lewy body,vascular and frontotemporal dementia,and hippocampal sclerosis in the state of Florida brain bank[J].Alzheimer Dis Assoc Disord,2002,16:203-12.
[6] Rockwood K,Wentzel C,Hachinski V,Hogan DB,MacKnight C,McDowell I.Prevalence and outcomes of vascular cognitive impairment.Vascular cognitive impairment investigators of the Canadian Study of Health and Aging[J].Neurology,2000,54:447-51.
[8] Pohjisvasarn T,Erkinjuntti T,Vataja R,et al.Dementia three months after stroke,baseline frequency and effect of different definition of dementia in the Helsinki Aaing Memory Study(SAM)cohort[J].Stroke,1997:28(4):785.
[9] Tatemichi TK,Desmond DW,Stern Y,et al.Cognitive impairment after stroke:frequency,patterns,and relationship to functional abilities[J].J Neurol Neurosurg Psychiatry,1994,57(2):202.
[10] Roman GC.Vascular dementia may be the most common form of dementia in the eldly[J].J Neurol,2001,8(6):621.
[11] Rockwood K.Vascular cognitive impairment and vascular dementia[J].Neurologist,2003,9:123-136.
[12] Wentzel C,Rockwood K,Hachinski V,et al.Progression of impairment in patients with vascular cognitive impairment without dementia[J] .JNeurology,2001,57(4):714.
[19] Tham W,Auchus AP,Thong M,et al.Progression of cognitive impairment after stroke:one year results from a longitudinal study of Singaporean stroke patients[J].J Neurol Sci,2002,203-204:49-52.
[20] Srikanth VK,Quinn SJ,Donnan GA,Saling MM,Thrift AG.Longterm cognitive transitions,rates of cognitive changes,and predictors of incident dementia in a population-based first-ever stroke cohort[J].Stroke,2006,37:2479-83.
[21] Nyenhuis DL.Vascular Cognitive Impairment:A Common Sequelae of Stoke and its Prevention[J].American Academy of Neurology,2000:145.
[22] Rockwood K,Black SE,Song X,et al.Clinical and radiographic subtypes of vascular cognitive impairment in a clinic-based cohort study[J].J Neurol Sci,2006,240:7-14.
[23] Wentzel C,Rockwood K,Macknight C,et al.Progression of impairment in patients with vascular cognitive impairment without dementia[J].J Neurology,2001,57:714-716.
[24] Abbott RD,Donahue RP,MacMahon SW,Reed DM,Yano K.Diabetes and the risk of stroke.The Honolulu Heart Program[J].JAMA,1987,257:949-52.
[25] Knopman D,Boland LL,Mosley T,et al.Cardiovascular risk factors and cognitive decline in middle-aged adults[J].Neurology,2001,56:42-48.
[26] Ott A,Stolk RP,Hofman A,van Harskamp F,Grobbee DE,Breteler MM,Association of diabetes mellitus and dementia:the Rotterdam Study[J].Diabetologia,1996,29:1392-97.
[29] Skog I.Risk factors for vascular dementia:review[J].Dementia.1994,5:137-144.
[30] Smith AD.Homocysteine,B vitamins,and cognitive deficit in the elderly[J].Am J Clin Nutr,2000,75:785-786.
[31] Forette F,Seux ML,Staessen JA,Thijs L,Babarskiene MR,Babeanu S,Bossini A,Fagard R,Gil-Extremera B,Laks T,Kobalava Z,Sarti C,Tuomilehto J,Vanhanen H,Webster J,Yodfat Y,Birkenhager WH.The prevention of dementia with antihypertensive treatment:new evidence from the Systolic Hypertension in Europe (Syst-Eur) study[J].Arch Intern Med,2002,162:2046-2052.
[32] Gorelick PB,Neuroprotection in acute ischemic stroke:a tale of for whom the bell toll[J]?Lancet,2000,355:1925-1926.
[33] Klijin CJ,Hankey GJ,American Stroke Association,European Stroke Initiative.Management of acute stroke:new guidelines from the American Stroke Association and the European Stroke Initiative[J].Lancet Neurol,2003,2:698-701.
[34] Gorelick PB.Stroke prevention therapy beyond antithrombotics:unifying mechanisms in ischemic stroke pathogenesis and implications for therapy[J].Stroke,2002,33:862-875.
[35] Moroney JT,Bagiella E,Desmond DW,Paik MC,SternY,Tatemichi TK.Risk factors for incident dementia after stroke:role of hypoxic ischemic disorders[J].Stroke,1996,27:1283-1289.
[36] Rockwood K,Darvesh S.The risk of dementia in relation to statins and other lipid lowering agents[J].Neurol Res,2003,25:601-604.
[37] Fassbender K,Simons M,Bergmann C,Stroick M,Lutjohann D,Keller P,Runz H,Kuhl S,Bertsch T,von Bergmann K,Hennerici M,Beyreuther K,Hartmann.Simvastatin strongly reduces levels of Alzheimer’s disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo[J].Proc Narl Accad Sci USA,2001,98:5856-5861.
[38] Darvesh S,Martin E,Walsh R,Rockwood K.Differential effects of lipid-lowering agents on human cholinesterases[J].Clin Biochem,2004,37:42-29.
[39] The PROGRESS Collaborative Group.Effects of blood pressure lowering with perindopril and cognitive decline in patients with cerebrovascular disease[J].Arch Intern Med,2003,163:1069-1075.
[57] O’Sullivan M,Lythgoe DJ,Pereira AC,et al.Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis[J].Neurology,2002,59:321-326.
[58] Pantoni L,del Ser T,Soglian AG,et al.Efficacy and safety of nimodipine in subcortical vascular dementia:a randomized placebo-controlled trial[J].Stroke,2005,36:619-624.
[59] Orgogozo JM,Rigaud AS,Stoffler A,et al.Efficacy and safety of memantine in patients with mild to moderate vascular dementia:a randomized,placebo-controlled trail(MMM 300) [J].Stroke,2002,33:1834-1839.
[60] Swartz RH,Sahlas DJ,Black SE.Strategic involvement of cholinergic pathways and executive dysfunction:Does location of white matter signal hyperintensities matter[J]?J Stroke Cerebrovasc Dis,2003,12:29-36.
[61] Erkinjuntti T,Inzitari D,Pantoni L,et al.Research criteria for subcortical vascular dementia in clinical trials[J].J Neural Transm Suppl,2000,59:23-30.
[62] Erkinjuntti T,Kurz A,Gauthier S,et al.Efficacy of galantamine in probable vascular dementia and Alzheimer’s disease combined with cerebrovascular disease:a randomized trial[J].Lancet,2002,359:1283-1290.
[63] Wilkinson D,Doody R,Helme R,et al.Donepezil 308 Study Group.Donepezil in vascular dementia:a randomized,placebo-controlled study[J].Neurology,2003,61:479-486.
[64] Demaerschalk BM,Wingerchuk DM.Treatment of Vascular Dementia and Vascular Cognitive Impairment[J].The Neurologist,2007,13(1):37-41.