"Liver-heat" refers to the pathogenesis of the stagnation of liver qi, which will dissipate heat over time and cause visceral dysfunction and qi disorder. Professor Ruan Shiwei classified it into a type of clinical syndrome, "liver fever" according to its clinical characteristics. He proposed that "liver heat" is the pathological basis of many internal injuries and miscellaneous diseases. The basic pathogenesis of this disease is "stagnation and blood stasis", and its treatment principles are "clearing, dispersing, permeating and guiding". Based on the above-mentioned theory, according to the principle of "clearly distinguishing qi and blood, three-burner treatment", the classical ancient prescriptions can be used flexibly to treat liver fever with significant curative effect. Ruan Shiwei’s clinical experience in diagnosis and treatment of liver fever is now compiled, and a case study is attached for supporting evidence.